If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

Together, these results reinforce the notion that PCNA and lagging-strand processes undergo functional exhaustion during unperturbed origin activation and become further depleted upon unscheduled ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Coronavirus (CoV) possesses numerous functional cis-acting elements in its positive-strand genomic RNA. Although most of these RNA structures participate in viral replication, the functions of RNA ...