Dengue is the most prevalent mosquito-borne viral disease in the world. Globally, about half of the world’s population is now at risk of dengue with an estimated 100–400 million infections occurring ...
Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
A central tenet of biology may need updating given new measurements of start codons. For decades, scientists working with genetic material have labored with a few basic rules in mind. To start, DNA is ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells
Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execute EMT programs in embryonic development and cancer. By studying regulation of their expression, we ...
While testing a new way to sequence genes, researchers stumbled upon a very rare divergence in the genetic code, which translates genetic sequences into proteins. The discovery was made in an organism ...
Conditional survival nomogram after an R0 resection for gastric cancer. Background: Recently, c-kit exon 11 deletions, including codons 557 and/or 558, have been reported to predict a worse prognosis ...
Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs). In ...
Alternative genetic decoding can be either a global phenomenon that affects the decoding of most or all mRNAs, or a local recoding that affects particular sites in a few mRNAs. Global alterations in ...
DURHAM, N.C. -- A new examination of the way different tissues read information from genes has discovered that the brain and testes appear to be extraordinarily open to the use of many different kinds ...
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