Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis ...

Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...

A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and ...

Mitochondria produce most of the cellular ATP by the process of oxidative phosphorylation (OXPHOS) and generate most of the endogenous oxygen radicals as a toxic by-product. In addition, mitochondria ...

NIMS, in collaboration with Nagoya University, Gifu University, and the University of Adelaide, has developed a method for simultaneously imaging DNA and RNA inside cells using harmless infrared to ...

BUFFALO, N.Y. -- A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in ...

DNA microarrays—devices that measure gene expression—could become easier to use, thanks to a new readout method based on electrostatic repulsion. Such devices are used in biological research and ...

Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

A*STAR scientists have developed a new method to directly and efficiently read DNA containing non-standard “letters” (bases) ...

Researchers from the Henry and Marilyn Taub Faculty of Computer Science have developed an AI-based method that accelerates DNA-based data retrieval by three orders of magnitude while significantly ...