Every cell type in the human body carries the same approximately 3.2 billion base pairs of DNA, yet a liver cell behaves nothing like a neuron. The epigenome explains this difference: in each cell, ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Differences in the pattern of a biochemical modification called DNA methylation in blood-generating cells and their progeny can be used to accurately track clones through differentiation. This ...

An international research team has recovered ancient human mitochondrial and nuclear DNA directly from cave wall materials in ...

Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...

Researchers benchmarked nanopore methylation callers across bacterial, plant, mouse, and human datasets, comparing accuracy, ...

It could be a saviour against disease, and a horrible weapon against humanity. There are no simple issues here. It’s a tough issue, and it just gets tougher. Genome editing (aka genome engineering) is ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Humans and their closest primate relatives diverged evolutionarily some 6 to 8 million years ago. Since then, a wide range of traits and behaviors have come to distinguish our species from the rest of ...