Researchers from the University College London have brought us one step closer to understanding how we feel pain. Their study, published in Brain, describes a rare genetic mutation found in a patient ...

Jo Cameron was 65 when she had hip replacement surgery. Her pain score afterward was zero out of ten. The following year, she ...

The research and development arm of Janssen Pharmaceuticals, a Johnson & Johnson company, announced on Sunday (January 17) their voluntary suspension of dosing in two Phase 2 clinical trials of their ...

Chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH). The enzyme has been considered for treatment for cannabis dependence because it breaks down substances ...

Figure 1: An overview of the endocannabinoid pathway and molecules tested in this study. “This study explores the functional relevance and therapeutic potential of FAAH inhibition combined with the ...

A woman in Scotland has been found to have a previously-unknown genetic mutation that makes her almost completely immune to pain, and on top of that her wounds heal faster and she seems to have ...

Doctors in Scotland were amazed when a 66-year-old woman underwent what is normally a very painful operation on her hand for severe arthritis and required little to no pain medication afterward.

The FDA is looking into the safety of one treatment from the FAAH inhibitor class after a patient died and 5 were severely injured--they took high doses of a drug from this class at the start of the ...

Fatty acid amide hydrolase (FAAH), an amidase-signature family member, is an integral membrane enzyme that degrades lipid amides including the endogenous cannabinoid anandamide and the sleep-inducing ...

A new study suggests that people who use both cannabis and tobacco have elevated levels of a key enzyme in their brain compared to people who only use cannabis. This finding may offer a biological ...