Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The ...

The latest chemistry news, including important research advances, business and policy trends, chemical safety practices, career guidance, and more. Expansion microscopy improves imaging resolution by ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds. In a new study, MIT chemical engineers have harnessed artificial ...

Progeria is a genetic condition that involves accelerated aging. Patients develop wrinkled skin, hair loss, and bone and joint stiffness from a very early age. One of the more unusual forms of this ...

Data from a new study in mice connects unrepaired DNA-protein crosslinks (DPCs), highly toxic tangles of protein and DNA, to inflammation-linked premature aging and embryonic lethality in mice. The ...