Yale researchers have discovered how megakaryocytes — giant blood cells that produce wound-healing platelets — manage to grow 10 to 15 times larger than other blood cells. The findings, to be ...

IN the course of a systematic search for tumor cells in the blood of patients with cancer of the female genital tract or of the head and neck areas, cells with the characteristics of megakaryocytes ...

Scientists from the Stowers Institute for Medical Research have discovered that megakaryocytes, best known for producing platelets that heal wounds, also play a critical role in regulating stem cells.

Megakaryocytes are the parent cells that make platelets—sticky bodies that circulate in the bloodstream and help the blood to clot when you get cut. They are also the culprits that contribute to clot ...

Figure 1: MK ablation impairs HSC quiescence and causes HSC proliferation. Figure 4: MKs support HSC expansion under stress through FGF1 signaling. Here we show that MKs, a derivative of HSCs, ...

Adipocytes can be converted into mesenchymal stem cells, which can then be converted into megakaryocytes. These megakaryocytes can be used to produce platelets, which may be a source of safer platelet ...

Using video microscopy in the living mouse lung, scientists have revealed that the lungs play a previously unrecognized role in blood production. Using video microscopy in the living mouse lung, UC ...

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, ...

A collaborative research team led by Dr. Thorsten Schlaeger (Boston Children's Hospital) Emiri Nakamura and Professor Koji Eto (Department of Clinical Application) has identified microtubule (MT) ...

Scientists found that megakaryocytes act as 'bouncers' and thus modulate bone marrow niche properties and cell migration dynamics. Hematopoiesis is the process of forming blood cells, which occurs ...