Non-inferiority trials are a valuable type of clinical trial to evaluate new treatments that might have differing benefits. Such trials are increasingly used, but have methodological challenges in ...

Non-inferiority trials have become an essential instrument in clinical research, particularly when the goal is to demonstrate that an experimental treatment is not unacceptably worse than an ...

The trials are evaluating DURAVYU (vorolanib intravitreal insert) for the treatment of diabetic macular edema (DME).

Ultrahypofractionated radiotherapy demonstrated non-inferiority to conventional fractionation with higher 10-year failure-free survival with similar toxicity profiles in patients with intermediate- or ...

(RTTNews) - Outlook Therapeutics, Inc. (OTLK), a biopharmaceutical company, on Thursday announced the completion of the 12-week efficacy and safety results from its NORSE EIGHT clinical trial for ...

Can AI match radiologists in prostate MRI diagnosis? The PARADIGM trial will assess AI detection of clinically significant ...

The NRG Oncology NRG-HN005 phase II/III clinical trial did not meet the non-inferiority criteria to proceed to the phase III portion of the study. The phase II portion of the NRG-HN005 evaluated two ...

Active Phase 3 programs for DURAVYU in wet AMD and DME, the two largest multi-billion-dollar retinal disease markets –– Topline data for ...

Topline results from a phase 3 clinical trial compared CagriSema with tirzepatide in patients with obesity. CagriSema is a fixed-dose combination of cagrilintide, a long-acting amylin analogue, ...

SAN ANTONIO -- Starches may be safe after all for fluid resuscitation in perioperative medicine, based on the PHOENICS non-inferiority trial addressing longstanding concerns from regulators and the ...