Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and ...

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia.

Increased plaque forming capability of N protein mutant viruses carrying either S202R or R203M mutations A recent paper by Syed et al. demonstrates that mutations in the Nucleocapsid (N) protein, one ...

Some genome editing systems are highly conspicuous. They introduce double-strand breaks to DNA that attract the attention of cellular mechanisms such as nonhomologous end joining and homology-directed ...

The first 100 bases of many genes show excess mutations, revealing a major genomic weak spot that shapes disease risk and highlights hidden patterns of inherited change.