Somatic copy number aberrations (SCNAs) are a hallmark of cancer, involving large-scale genomic alterations that drive tumorigenesis and cancer progression by affecting gene dosage and altering the ...
Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal ...
The architecture of a tissue determines its function and malfunction in health and disease. Therefore, technologies to study the spatial organization of cells and molecules in tissues are fundamental ...