Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...

In this corner: the state-of-the-art enzyme function prediction tool … the Bioinformatic Brawler … the Basic Local Alignment Search Tool for proteins … BLASTp! And in this corner: the contender … the ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for enzyme ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...