A landmark invited review published in Genomic Psychiatry provides a comprehensive synthesis to date of tau protein's complex roles in both health and disease. Dr. Peng Lei of Sichuan University and ...

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...

Much ado has been made of the neuronal damage inflicted by aggregates of tau, but what about the cost of losing normal tau protein to these proteopathic snarls? In the June 26 Journal of Experimental ...

The traditional view of tau is that of a rather dull microtubule-binding protein that occasionally goes rogue, wandering off into other cellular compartments where it stokes neurodegeneration. At ...

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its ...

Tau proteins are proteins that perform the function of stabilizing microtubules. These proteins are abundant in nerve cells and are present to a much lesser degree in oligodendrocytes and astrocytes.

In Alzheimer’s Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...

Tau is a microtubule-associated protein, which is widely expressed in the central nervous system, predominantly in neurons, where it regulates microtubule dynamics, axonal transport, and neurite ...