Until recently, little was known about how transposable elements contribute to gene regulation. These are little pieces of DNA that can replicate themselves and spread out in the genome. Although they ...

A new study shows that transposable elements play an important role in regulating genetic expression with implications to advance the understanding of genetic evolution. Until recently, little was ...

Researchers in Michigan published a study “Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes” in Nature Communications that shows ...

Mammalian genomes have been colonised by transposable elements (TEs), so called ‘genetic parasites’, which occupy ~ 50% of genomic DNA and harbour the potential to propagate, resulting in genetic ...

Whole-genomic sequencing has revolutionized the amount and detail of genetic diversity now available to researchers to study. While the researchers previously had looked at a few hundred mobile ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Molecular-Level Dissection ...

Mobile elements are DNA sequences that can move around the genome, changing their number of copies or simply changing their location, often affecting the activity of nearby genes. They include DNA ...

Ancient viruses are embedded everywhere in the human genome. Estimates range, but it's thought that about eight percent of the human genome could be made up of these ancient retroviruses, which are ...

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors ...

The MuDR/Mu transposons of maize are the most aggressive DNA transposons known in terms of their ability to increase the forward mutation frequency by ~ 100-fold. Their activities are held in check by ...