This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, ...

The intricate regulation of receptor tyrosine kinases (RTKs) underpins a vast array of cellular responses that are essential for growth, differentiation and survival. In particular, the interplay ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns. Scientists at St. Jude Children's ...

In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. But there are hundreds of ...

Hyperactive signaling pathways of some aggressive blood cancer cells can be tamped down by a previously unrecognized protein complex, ensuring the cancer's survival. If one component of the complex is ...

Two related studies from the University of California, Riverside, have reported that reduced activity of the PTPN2 gene ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

The field of plant stress biology has become increasingly crucial as climate change drives heightened frequencies and severities of abiotic stresses such as ...