This is a preview. Log in through your library . Abstract A monoclonal antibody (anti-αsm-1) recognizing exclusively α-smooth muscle actin was selected and characterized after immunization of BALB/c ...

smooth muscle α-actin; smooth muscle cells in blood vessel walls, gut wall, myometrium and arrectores pili of skin also myoepithelial cells found in breast and salivary gland ...

Actin-based gels were prepared from clarified high-salt extracts of human platelets by dialysis against physiological salt buffers. The gel was partially solubilized with 0.3 M KCl. Mice were ...

Smooth muscle differentiation is induced in the embryonic bladder by the centrally located urothelium in the undifferentiated mesenchyme in the periphery adjacent to the serosa. We hypothesize that ...

Autoimmune hepatitis type 1 (AIH-1) is a rare but serious liver disease characterized by specific autoantibodies, including those against filamentous actin (F-actin). Traditional testing relies on ...

We all age. And while humanity's life expectancy has increased dramatically in the modern era, we still struggle with the inevitable health issues our bodies face as we get up in the years. For ...

Non-human primate pharmacokinetics data suggests IBIO-600, a potentially best-in-class long-acting anti-myostatin antibody, could have a human half-life as long as 130 days Additional interim in vivo ...

Activin E antibody demonstrates significant decrease in fat in obese mice by reducing visceral fat depots, which are strongly linked to increased risk of cardiovascular and metabolic diseases, ...

Aging and limited physical activity, as well as the use of novel weight loss drugs such as Wegovy and Zepbound, often lead to the simultaneous loss of muscle mass and bone density. Medications are ...