Efforts to estimate the reproducibility of published research results have focused on specific areas of research to date, ...

This useful study explores the role of RAP2A in asymmetric cell division (ACD) regulation in glioblastoma stem cells (GSCs), drawing parallels to Drosophila ACD mechanisms and proposing that an ...

Microfluidics experiments and simulations show that magnetotactic bacteria are adapted to the geomagnetic field strength for optimal navigation in sediment environments.

This valuable study provides insights into a key question in comparative neuroanatomy and development. The authors provide evidence of the role for a particular micro-RNA in regulating the development ...

Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.

Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.

This is an important study utilizing innovative CRISPR based approaches demonstrating the role of the KLF family of transcription factors in the post natal maturation of cortical projection neurons.

Pannexin (Panx) channels are a family of poorly understood large-pore channels that mediate the release of substrates like ATP from cells, yet the physiological stimuli that activate these channels ...

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

This valuable study shows that mutations in specific cassava genes can reduce infection by cassava brown streak viruses. The authors also identify a key amino acid change that may be significant in ...