Myokines are hormones that communicate via the bloodstream with various organs such as the brain, adipose tissue, liver, bone ...

Calorie restriction lowers C3, an immune protein tied to aging and inflammation, improving health without requiring weight ...

One of India’s four navigation satellites has gone out of service, creating a fresh problem for the NavIC network. ISRO said ...

Jay O. Rothman’s departure brought an end to a four-year stint as leader of the university system following a public struggle for power. By Alan Blinder and Stephanie Saul The board of Wisconsin’s ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that is also considered an autoimmune disorder. There is no single cure for C3G, but several treatments may slow disease progression, protect ...

Also called C3G, this rare kidney disease often affects children and young adults, but it can happen at any age. It has a major impact on a person’s health and life. C3G has two forms: dense deposit ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Mass General Brigham researchers found granzyme K (GZMK) drives inflammation in autoimmune diseases, opening new possibilities for targeted treatments. Researchers at Mass General Brigham have made a ...