In recent decades it has become routine to describe asthma as an atopic disease. A theoretical paradigm has evolved in which allergen exposure produces atopic sensitisation and continued exposure ...

A 9-year-old girl presented with a 9-week history of persistent coughing. She was HIV-negative, had no prior health issues, no history of asthma or recurrent infections and reported no known contact ...

Exercise tolerance predicts survival and mental health. To test benefits during adolescence for patients with pulmonary arteriovenous malformations (PAVMs) that cause hypoxaemia, we examined current ...

Exacerbations of COPD are thought to be caused by complex interactions between the host, bacteria, viruses, and environmental pollution. These factors increase the inflammatory burden in the lower ...

Introduction The gender-age-physiology (GAP) index is an easy-to-use baseline mortality prediction model in idiopathic pulmonary fibrosis (IPF). The GAP index does not incorporate exercise capacity ...

Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with increased morbidity and mortality. The effective management of COPD exacerbations awaits a better understanding of the ...

Background Switching inhalers to cheaper equivalent products is often advocated as a necessary cost saving measure, yet the impact on patient’s health and healthcare utilisation has not been measured.

The COVID-19 pandemic has led to an unprecedented surge in hospitalised patients with viral pneumonia. The most severely affected patients are older men, individuals of black and Asian minority ...

To evaluate the effectiveness of the Centers for Disease Control and Prevention (CDC) recommended one- and two-layer cloth face covering against a three-ply surgical mask, we challenged the cloth ...

The clinical presentation of Aspergillus lung disease is determined by the interaction between fungus and host. Invasive aspergillosis develops in severely immunocompromised patients, including those ...

Rationale OPEP devices are often used therapeutically in order to aid airway clearance where excess mucus is a challenge, such as in bronchiectasis, CF and COPD. Ease of use, ability to clean and ...