3D model generated from tomogram virtual slices of a wild-type presynaptic terminal active zone. Modeled features include the cytomatrix (blue), synaptic vesicles (clustered pool in gray, vesicles in contact with the cytomatrix in orange, release-ready vesicles in contact with the cytomatrix in magenta, and release-ready vesicles distal to the cytomatrix in olive), tethers linking synaptic vesicles to the plasma membrane (purple), and connectors between synaptic vesicles (green). Video © Bruckne
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